Mother's Age, Race, Weight Affect Hormone, Concentrations In Pregnancy.. - Secret News

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Tuesday, 12 February 2019

Mother's Age, Race, Weight Affect Hormone, Concentrations In Pregnancy..

Mother's Age, Race, Weight, Affect Hormone, Concentrations In Pregnancy..


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The researchers looked at the concentrations of estrogens and testosterone in 548 healthy women in the first trimester of pregnancy in relation to their lifestyle to better understand what drives elevated sex hormones during fetal development.




"Hormones in early development play a key role in human health and disease risk. Since we are unable to directly measure hormones in fetuses as they are developing, the next best way is to study the mother's hormones since they can be transferred to the fetus," said Emily Barrett, an associate professor at Rutgers School of Public Health and a faculty member at Rutgers Environmental and Occupational Health Sciences Institute.

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Previous studies have suggested that excess fetal exposure to estrogens and androgens, which are male sex hormones such as testosterone, may play a role in future risk of reproductive cancers and other conditions such as polycystic ovary syndrome, endometriosis, prostate cancer and semen quality in the infant.






In the new study, researchers recruited women during early pregnancy and collected a blood sample to measure hormones. The participants completed questionnaires with items on demographics as well as lifestyle factors, including their alcohol or tobacco use, and stressors in their lives,


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Most of the women were white, married, well-educated and had an average age of 31. Less than 5 percent drank alcohol and less than 8 percent smoked. The researchers found that older mothers and women who had previously given birth had lower estrogen and testosterone levels.




They also found that heavier women had lower estrogen levels, but higher testosterone levels than leaner women. Confirming results from previous work, they found that black women had higher testosterone levels than women of other races, a difference that may help to explain health disparities in reproductive cancers and other hormone-sensitive diseases.

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